It is still important that she make a hefsek taharah, observe seven clean days, and immerse in a mikveh within four days of the wedding and schedule accordingly. As you wrote, there is no requirement to separate after the first act of relations. In some ways, this simplifies timing, since she will not try to schedule for her period to arrive soon after the wedding. Also, the ketubah will not read "betulah." If it is a second wedding for both the bride and groom, sheva brachot will be recited on the day of the wedding, but not during the week that follows.
We cannot think of other halachic differences. There may be some differences in wedding customs, depending on the community; this should be discussed with the officiating rabbi.